131167-89-0
131167-89-0
Chemical Structure
H-Ile-Lys-Val-Ala-Val-OH
- CAS. Nr.: 131167-89-0
- Formula:C25H48N6O6
- Molecular Weight:528.69
InChIKey: XQQUSYWGKLRJRA-RABCQHRBSA-N
SMILES: CC(C)[C@@H](C(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)=O
Biological Activity: H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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H-Ile-Lys-Val-Ala-Val-OH | 99.35% | H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways. | ||||||||||||||||||||
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References
- [1]. Nomizu M, et al. The all-D-configuration segment containing the IKVAV sequence of laminin A chain has similar activities to the all-L-peptide in vitro and in vivo. J Biol Chem. 1992 Jul 15;267(20):14118-21. [Content Brief]
- [2]. Li B, et al. IKVAV regulates ERK1/2 and Akt signalling pathways in BMMSC population growth and proliferation. Cell Prolif. 2014 Apr;47(2):133-45. [Content Brief]
