132812-45-4
Chemical Structure
Blonanserin dihydrochloride
Synonym(s): AD-5423 dihydrochloride
- CAS No.: 132812-45-4
- Formula:C23H32Cl2FN3
- Molecular Weight:440.42
IUPAC Name: 2-(4-ethylpiperazin-1-yl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine dihydrochloride
InChIKey: IQTIXQWMIKSCBX-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2=C(CCCCCC3)C3=NC(N4CCN(CC)CC4)=C2)C=C1.Cl.Cl
Biological Activity: Blonanserin dihydrochloride is a potent and orally active 5-HT2A and dopamine D2 receptor antagonist, with Ki values of 0.812 and 0.142 nM, respectively. Blonanserin dihydrochloride is usually acts as an atypical antipsychotic agent, and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension[1][2].
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Blonanserin dihydrochloride | Blonanserin dihydrochloride is a potent and orally active 5-HT2A and dopamine D2 receptor antagonist, with Ki values of 0.812 and 0.142 nM, respectively. Blonanserin dihydrochloride is usually acts as an atypical antipsychotic agent, and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension. | |||||||||||||||||||||
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Keywords