1342890-83-8
1342890-83-8
Chemical Structure
Arylsulfonamide 64B
Synonym(s): HIF inhibitor 64B
- CAS No.: 1342890-83-8
- Formula:C23H28N2O5S
- Molecular Weight:444.54
IUPAC Name: N-cyclobutyl-N-((2,2-dimethyl-2H-pyrano[3,2-b]pyridin-6-yl)methyl)-3,4-dimethoxybenzenesulfonamide
InChIKey: CQGIUFASDNXPRB-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(OC)C(OC)=C1)(N(C2CCC2)CC3=CC=C4C(C=CC(C)(C)O4)=N3)=O
Biological Activity: Arylsulfonamide 64B (HIF inhibitor 64B) is an inhibitor of the hypoxia-induced factor (HIF). Arylsulfonamide 64B inhibits hypoxia/HIF-induced expression of c-Met and CXCR4 and reduces primary tumor growth and metastasis of uveal melanoma mouse model[1].
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Arylsulfonamide 64B | Arylsulfonamide 64B (HIF inhibitor 64B) is an inhibitor of the hypoxia-induced factor (HIF). Arylsulfonamide 64B inhibits hypoxia/HIF-induced expression of c-Met and CXCR4 and reduces primary tumor growth and metastasis of uveal melanoma mouse model. | |||||||||||||||||||||
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