2. Metabolic Enzyme/Protease
  3. HIF/HIF Prolyl-Hydroxylase
  4. Arylsulfonamide 64B

Arylsulfonamide 64B  (Synonyms: HIF inhibitor 64B)

Cat. No.: HY-124875
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Arylsulfonamide 64B (HIF inhibitor 64B) is an inhibitor of the hypoxia-induced factor (HIF). Arylsulfonamide 64B inhibits hypoxia/HIF-induced expression of c-Met and CXCR4 and reduces primary tumor growth and metastasis of uveal melanoma mouse model.

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Arylsulfonamide 64B Chemical Structure

Arylsulfonamide 64B Chemical Structure

CAS No. : 1342890-83-8

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Arylsulfonamide 64B Related Antibodies

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Description

Arylsulfonamide 64B (HIF inhibitor 64B) is an inhibitor of the hypoxia-induced factor (HIF). Arylsulfonamide 64B inhibits hypoxia/HIF-induced expression of c-Met and CXCR4 and reduces primary tumor growth and metastasis of uveal melanoma mouse model[1].

Molecular Weight

444.54

Formula

C23H28N2O5S
CAS No.
SMILES

O=S(C1=CC=C(OC)C(OC)=C1)(N(C2CCC2)CC3=CC=C4C(C=CC(C)(C)O4)=N3)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Arylsulfonamide 64B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Arylsulfonamide 64B1342890-83-8HIF inhibitor 64BHIF/HIF Prolyl-HydroxylaseHypoxia-inducible factorsHIFsHIF-PHHIFuveal melanomametastasisCXCR4c-Metarylsulfonamideexperimental therapeuticsdrug discoveryInhibitorinhibitorinhibit

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