136451-58-6
136451-58-6
Chemical Structure
BMY 42393
- CAS No.: 136451-58-6
- Formula:C25H21NO4
- Molecular Weight:399.44
IUPAC Name: 2-(3-(2-(4,5-diphenyloxazol-2-yl)ethyl)phenoxy)acetic acid
InChIKey: AZZHJQQOAHWBPN-UHFFFAOYSA-N
SMILES: O=C(O)COC1=CC=CC(CCC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)O2)=C1
Biological Activity: BMY 42393 is an orally active prostacyclin agonist which suppresses monocyte-macrophage atherogenic activity and cytokine production. BMY 42393 can be used for atherosclerosis research[1].
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BMY 42393 | BMY 42393 is an orally active prostacyclin agonist which suppresses monocyte-macrophage atherogenic activity and cytokine production. BMY 42393 can be used for atherosclerosis research. | |||||||||||||||||||||
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References
- [1]. Kowala MC, et al. Prostacyclin agonists reduce early atherosclerosis in hyperlipidemic hamsters. Octimibate and BMY 42393 suppress monocyte chemotaxis, macrophage cholesteryl ester accumulation, scavenger receptor activity, and tumor necrosis factor production. Arterioscler Thromb. 1993 Mar;13(3):435-44. [Content Brief]
