1369503-03-6
1369503-03-6
Chemical Structure
COX-1-IN-1
- CAS No.: 1369503-03-6
- Formula:C20H21NO3
- Molecular Weight:323.39
InChIKey: BCOIWKZLSWINMZ-UHFFFAOYSA-N
SMILES: CCOC1=CC=C(C2=NOC(C)=C2C3=CC=C(OCC)C=C3)C=C1
Biological Activity: COX-1-IN-1 (compound 15a) is a selective inhibitor for cyclooxygenase (COX), with IC50s of 0.23 μM (COX-1) and >50 μM (COX-2), selective index (COX-2 IC50/COX-1 IC50) is 217. COX-1-IN-1 inhibits platelet aggregation[1].
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COX-1-IN-1 | COX-1-IN-1 (compound 15a) is a selective inhibitor for cyclooxygenase (COX), with IC50s of 0.23 μM (COX-1) and >50 μM (COX-2), selective index (COX-2 IC50/COX-1 IC50) is 217. COX-1-IN-1 inhibits platelet aggregation. | |||||||||||||||||||||
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