13860-38-3
Chemical Structure
N1-Methylpseudouridine
Synonym(s): 1-Methylpseudouridine; N1-methyl-pseudouridine
- CAS No.: 13860-38-3
- Formula:C10H14N2O6
- Molecular Weight:258.23
IUPAC Name: 5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: UVBYMVOUBXYSFV-XUTVFYLZSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O1
Biological Activity: N1-methyl-pseudouridine (1-Methylpseudouridine), a methylpseudouridine, outperforms 5 mC and 5 mC/N1-methyl-pseudouridine in translation. N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N1-Methylpseudouridine | 99.97% | N1-methyl-pseudouridine (1-Methylpseudouridine), a methylpseudouridine, outperforms 5 mC and 5 mC/N1-methyl-pseudouridine in translation. N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density. | ||||||||||||||||||||
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N1-Methylpseudouridine-d3 | N1-Methylpseudouridine-d3 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Similarity Score 0.87
HY-152767N1-Ethylpseudouridine -
Similarity Score 0.84
HY-152342N1-Methoxymethyl pseudouridine -
Similarity Score 0.84
HY-1528371,3-Dimethyl pseudouridine -
Similarity Score 0.83
HY-1528533-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione -
Similarity Score 0.83
HY-152659N1-Propargylpseudouridine -
Similarity Score 0.83
HY-152609N1-Cyanomethyl pseudouridine -
Similarity Score 0.83
HY-154674N1-Allylpseudouridine -
Similarity Score 0.81
HY-178571N1-Me-pUMP -
Similarity Score 0.81
HY-113061Pseudouridine -
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