13860-38-3
Chemical Structure
N1-Methylpseudouridine
Synonym(s): 1-Methylpseudouridine; N1-methyl-pseudouridine
- CAS. Nr.: 13860-38-3
- Formula:C10H14N2O6
- Molecular Weight:258.23
IUPAC Name: 5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: UVBYMVOUBXYSFV-XUTVFYLZSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O1
Biological Activity: N1-methyl-pseudouridine (1-Methylpseudouridine), a methylpseudouridine, outperforms 5 mC and 5 mC/N1-methyl-pseudouridine in translation. N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density[1].
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N1-Methylpseudouridine | 99.97% | N1-methyl-pseudouridine (1-Methylpseudouridine), a methylpseudouridine, outperforms 5 mC and 5 mC/N1-methyl-pseudouridine in translation. N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density. | ||||||||||||||||||||
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N1-Methylpseudouridine-d3 | N1-Methylpseudouridine-d3 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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