13956-53-1
Chemical Structure
24-O-Acetyllycoclavanol
- CAS No.: 13956-53-1
- Formula:C32H52O4
- Molecular Weight:500.75
InChIKey: URQDZURTBUEWHZ-ZBNXLKIRSA-N
SMILES: C[C@@]12[C@](CC[C@@]3([C@]2([H])CC[C@@]4([H])C(C3)=CC[C@]5([H])[C@@]4(CC[C@H](C5(C)C)O)C)C)([H])[C@](C)([C@@H](CC1)O)COC(C)=O
Biological Activity: 24-O-Acetyllycoclavanol (compound 1) is a triterpenoid anti-inflammatory agent that selectively targets the NF-κB and ERK1/2 signaling pathways. It exerts its anti-inflammatory activity by inhibiting lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) and COX-2 expression, reducing the production of inflammatory mediators such as nitric oxide (NO), IL-1β, and IL-8. 24-O-Acetyllycoclavanol can be used in research related to inflammatory bowel disease (IBD). 24-O-Acetyllycoclavanol can be biologically isolated from the ethyl acetate extract of Lycopodium clavatum[1].
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24-O-Acetyllycoclavanol | 24-O-Acetyllycoclavanol (compound 1) is a triterpenoid anti-inflammatory agent that selectively targets the NF-κB and ERK1/2 signaling pathways. It exerts its anti-inflammatory activity by inhibiting lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) and COX-2 expression, reducing the production of inflammatory mediators such as nitric oxide (NO), IL-1β, and IL-8. 24-O-Acetyllycoclavanol can be used in research related to inflammatory bowel disease (IBD). 24-O-Acetyllycoclavanol can be biologically isolated from the ethyl acetate extract of Lycopodium clavatum. | |||||||||||||||||||||
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Keywords
