1395946-75-4
1395946-75-4
Chemical Structure
APX-115
Synonym(s): Ewha-18278
- CAS No.: 1395946-75-4
- Formula:C17H18ClN3O
- Molecular Weight:315.80
IUPAC Name: 3-phenyl-4-propyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol hydrochloride
InChIKey: GMFJXGGAGPCRBM-UHFFFAOYSA-N
SMILES: OC1=C(CCC)C(C2=CC=CC=C2)=NN1C3=NC=CC=C3.Cl
Biological Activity: APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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APX-115 | 99.90% | APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury. | ||||||||||||||||||||
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References
Keywords
