1401436-95-0
Chemical Structure
Zandelisib
Synonym(s): ME-401; PWT-143
- CAS No.: 1401436-95-0
- Formula:C31H38F2N8O
- Molecular Weight:576.68
IUPAC Name: 4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-N-(2-methyl-1-(2-(1-methylpiperidin-4-yl)phenyl)propan-2-yl)-6-morpholino-1,3,5-triazin-2-amine
InChIKey: WPFUFWIHMYZXSF-UHFFFAOYSA-N
SMILES: CN1CCC(C2=CC=CC=C2CC(NC3=NC(N4C5=CC=CC=C5N=C4C(F)F)=NC(N6CCOCC6)=N3)(C)C)CC1
Biological Activity: Zandelisib (ME-401) is a selective, orally active, non-covalent inhibitor of PI3Kδ. Zandelisib can sustainably inhibit AKT phosphorylation and downstream signaling pathways. Zandelisib can be used in the study of malignancies such as relapsed/refractory B-cell lymphoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Zandelisib | 99.67% | Zandelisib (ME-401) is a selective, orally active, non-covalent inhibitor of PI3Kδ. Zandelisib can sustainably inhibit AKT phosphorylation and downstream signaling pathways. Zandelisib can be used in the study of malignancies such as relapsed/refractory B-cell lymphoma. | ||||||||||||||||||||
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Zandelisib (Standard) | ≥98% | Zandelisib (Standard) is the analytical standard of Zandelisib (HY-109198). This product is intended for research and analytical applications. Zandelisib (ME-401) is a selective, orally active, non-covalent inhibitor of PI3Kδ. Zandelisib can sustainably inhibit AKT phosphorylation and downstream signaling pathways. Zandelisib can be used in the study of malignancies such as relapsed/refractory B-cell lymphoma. | ||||||||||||||||||||
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Similarity Score 0.91
HY-150019PI3K-IN-36 -
Similarity Score 0.80
HY-114428P110δ-IN-1 -
Similarity Score 0.67
HY-120265MIPS-9922 -
Similarity Score 0.64
HY-50847ZSTK474 -
Similarity Score 0.61
HY-143403PI3K-IN-31 -
Similarity Score 0.61
HY-143404PI3K-IN-30 -
Similarity Score 0.55
HY-157125PI3Kα-IN-14 -
Similarity Score 0.55
HY-123790AS2541019 -
Similarity Score 0.54
HY-123849SN32976 -
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