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Zandelisib 

Cat. No.: HY-109198
Handling Instructions

Zandelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor extracted from patent WO2019183226 A1, Compound Example 1. Zandelisib selectively inhibits p110δ with an IC50 of 3.5 nM. Zandelisib functions as an antineoplastic.

For research use only. We do not sell to patients.

Zandelisib Chemical Structure

Zandelisib Chemical Structure

CAS No. : 1401436-95-0

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Description

Zandelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor extracted from patent WO2019183226 A1, Compound Example 1. Zandelisib selectively inhibits p110δ with an IC50 of 3.5 nM. Zandelisib functions as an antineoplastic[1][2].

IC50 & Target

PI3Kδ

3.5 nM (IC50)

In Vitro

Zandelisib inhibits PI3Ks with IC50s of 4, 976 nM, 605 nM, 817 nM and 3.5 nM for p110α, p110β, p110γ and p110δ, respectivey[1].

Molecular Weight

576.68

Formula

C₃₁H₃₈F₂N₈O

CAS No.

1401436-95-0

SMILES

CN1CCC(C2=CC=CC=C2CC(NC3=NC(N4C5=CC=CC=C5N=C4C(F)F)=NC(N6CCOCC6)=N3)(C)C)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

ZandelisibPI3KPhosphoinositide 3-kinasePhosphatidylinositol3-kinasep110δantineoplasticInhibitorinhibitorinhibit

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