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Cat. No.: HY-109198R

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Zandelisib (Standard)

(Synonyms: ME-401 (Standard); PWT-143 (Standard))

Zandelisib (Standard) is the analytical standard of Zandelisib (HY-109198). This product is intended for research and analytical applications. Zandelisib (ME-401) is a selective, orally active, non-covalent inhibitor of PI3Kδ. Zandelisib can sustainably inhibit AKT phosphorylation and downstream signaling pathways. Zandelisib can be used in the study of malignancies such as relapsed/refractory B-cell lymphoma.

For research use only. We do not sell to patients.

CAS No.: 1401436-95-0
Formula: C₃₁H₃₈F₂N₈O
Molecular Weight:576.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Zandelisib (Standard) Chemical Structure

CAS No.: 1401436-95-0

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1401436-95-0
Molecular Weight 576.68
Formula C₃₁H₃₈F₂N₈O
SMILES

CN1CCC(C2=CC=CC=C2CC(NC3=NC(N4C5=CC=CC=C5N=C4C(F)F)=NC(N6CCOCC6)=N3)(C)C)CC1
Synonyms

ME-401 (Standard); PWT-143 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kunieda K, et al. A long-lasting PI3Kδ inhibitor zandelisib forms a water-shielded hydrogen bond with p110δ and demonstrates sustained inhibitory effects. Am J Cancer Res. 2025 May 15;15(5):2097-2110. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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