141022-99-3
141022-99-3
Chemical Structure
PACOCF3
Synonym(s): Palmityltrifluoromethylketone
- CAS No.: 141022-99-3
- Formula:C17H31F3O
- Molecular Weight:308.42
IUPAC Name: 1,1,1-trifluoroheptadecan-2-one
InChIKey: MAHYXYTYTLCTQD-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCC(C(F)(F)F)=O
Biological Activity: PACOCF3 (Palmityltrifluoromethylketone) is a selective phospholipase A2 inhibitor with an IC50 of 3.8 μM. PACOCF3 alters Ca2+ signaling in renal tubular cells[1][2].
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PACOCF3 | 98.0% | PACOCF3 (Palmityltrifluoromethylketone) is a selective phospholipase A2 inhibitor with an IC50 of 3.8 μM. PACOCF3 alters Ca2+ signaling in renal tubular cells. | ||||||||||||||||||||
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PACOCF3 (Standard) | ≥98% | PACOCF3 (Standard) is the analytical standard of PACOCF3. This product is intended for research and analytical applications. PACOCF3 (Palmityltrifluoromethylketone) is a selective phospholipase A2 inhibitor with an IC50 of 3.8 μM. PACOCF3 alters Ca2+ signaling in renal tubular cells. | ||||||||||||||||||||
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References
- [1]. E J Ackermann, et al. Inhibition of macrophage Ca(2+)-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones. J Biol Chem. 1995 Jan 6;270(1):445-50. [Content Brief]
- [2]. C R Jan, et al. Dual action of palmitoyl trifluoromethyl ketone (PACOCF3) on Ca2+ signaling: activation of extracellular Ca2+ influx and alteration of ATP- and bradykinin-induced Ca2+ responses in Madin Darby canine kidney cells. Arch Toxicol. 2000 Oct;74(8):447-51. [Content Brief]
Keywords
