1428652-16-7
1428652-16-7
Chemical Structure
(S)-Baxdrostat
Synonym(s): (S)-CIN-107
- CAS No.: 1428652-16-7
- Formula:C22H25N3O2
- Molecular Weight:363.45
IUPAC Name: triethyl stibenite
InChIKey: VDEUDSRUMNAXJG-IBGZPJMESA-N
SMILES: CCC(N[C@@H]1C2=CN=CC(C3=CC=C(N(C(CC4)=O)C)C4=C3)=C2CCC1)=O
Biological Activity: (S)-Baxdrostat ((S)-CIN-107) is the S-enantiomer of Baxdrostat (HY-132809). Baxdrostat is a highly selective and potent inhibitor of Aldosterone synthase. Baxdrostat can be used in research on resistant hypertension[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S)-Baxdrostat | 98.84% | (S)-Baxdrostat ((S)-CIN-107) is the S-enantiomer of Baxdrostat (HY-132809). Baxdrostat is a highly selective and potent inhibitor of Aldosterone synthase. Baxdrostat can be used in research on resistant hypertension. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-132809Baxdrostat -
Similarity Score 1.00
HY-132809B(Rac)-Baxdrostat -
Similarity Score 0.65
HY-176480CYP11B2-IN-3 -
Similarity Score 0.46
HY-124382AS1928370 -
Similarity Score 0.45
HY-164781KOTX1 -
Similarity Score 0.44
HY-174270NLRP3-IN-79 -
Similarity Score 0.44
HY-112136TAO Kinase inhibitor 1 -
Similarity Score 0.44
HY-19478TAK-802 -
Similarity Score 0.43
HY-101217BI 689648 -
Explore the MedChemAI to find more analogs
References
- [1]. International Nonproprietary Names for Pharmaceutical Substances (INN).
- [2]. Freeman MW, et al. Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension. N Engl J Med. 2023 Feb 2;388(5):395-405.
- [3]. Jhaveri KD, et al. Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension. N Engl J Med. 2026 Jan 15;394(3):305.
