1431697-90-3
1431697-90-3
Chemical Structure
SB-408124 Hydrochloride
- CAS No.: 1431697-90-3
- Formula:C19H19ClF2N4O
- Molecular Weight:392.83
IUPAC Name: 1-(6,8-difluoro-2-methylquinolin-4-yl)-3-(4-(dimethylamino)phenyl)urea hydrochloride
InChIKey: DIHXPSGMLOETTI-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C=C1)N(C)C)NC2=CC(C)=NC(C2=CC(F)=C3)=C3F.[H]Cl
Biological Activity: SB-408124 Hydrochloride is a selective non-peptide orexin receptor 1 (OX1) receptor antagonist with Kis of 57 nM and 27 nM in whole cell and membrane, respectively. SB-408124 Hydrochloride exhibits 50-fold selectivity over OX2 receptor[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SB-408124 Hydrochloride | 98.79% | SB-408124 Hydrochloride is a selective non-peptide orexin receptor 1 (OX1) receptor antagonist with Kis of 57 nM and 27 nM in whole cell and membrane, respectively. SB-408124 Hydrochloride exhibits 50-fold selectivity over OX2 receptor. | ||||||||||||||||||||
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SB-408124 Hydrochloride (Standard) | ≥98% | SB-408124 (Hydrochloride) (Standard) is the analytical standard of SB-408124 (Hydrochloride). This product is intended for research and analytical applications. SB-408124 Hydrochloride is a selective non-peptide orexin receptor 1 (OX1) receptor antagonist with Kis of 57 nM and 27 nM in whole cell and membrane, respectively. SB-408124 Hydrochloride exhibits 50-fold selectivity over OX2 receptor. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-70068SB-408124 -
Similarity Score 0.56
HY-13686PQ401 -
Similarity Score 0.55
HY-122704ASurfen dihydrochloride -
Similarity Score 0.55
HY-122704Surfen -
Similarity Score 0.53
HY-106399AAcodazole hydrochloride -
Similarity Score 0.52
HY-106399Acodazole -
Similarity Score 0.52
HY-112693H-151 -
Similarity Score 0.51
HY-156449STING-IN-7 -
Similarity Score 0.50
HY-D0942Acridine Orange zinc chloride salt -
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