143631-62-3
Chemical Structure
Ciprokiren
Synonym(s): Ro 44-9375
- CAS No.: 143631-62-3
- Formula:C37H55N5O8S
- Molecular Weight:729.93
SMILES: O=C(N1CCOCC1)C(C)(C)S(C[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H]([C@@H](O)[C@H](C3CC3)O)CC4CCCCC4)=O)CC5=CN=CN5)=O)(=O)=O
Biological Activity: Ciprokiren (Ro 44-9375) is a Renin inhibitor with IC50s of 0.07 and 0.65 nM for hRenin in buffer and plasma, respectively. Ciprokiren be applied transdermally with similar hemodynamic effects without decrease of plasma renin activity or plasma immunoreactive angiotensin II. Ciprokiren has antihypertensive efficacy and can be used for hypertension research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Ciprokiren | Ciprokiren (Ro 44-9375) is a Renin inhibitor with IC50s of 0.07 and 0.65 nM for hRenin in buffer and plasma, respectively. Ciprokiren be applied transdermally with similar hemodynamic effects without decrease of plasma renin activity or plasma immunoreactive angiotensin II. Ciprokiren has antihypertensive efficacy and can be used for hypertension research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
