1445901-41-6
1445901-41-6
Chemical Structure
RORγt inverse agonist 30
- CAS No.: 1445901-41-6
- Formula:C24H31N3O3S
- Molecular Weight:441.59
IUPAC Name: N-(4-(4-acetylpiperazin-1-yl)benzyl)-N-cyclobutyl-1-phenylmethanesulfonamide
InChIKey: KIHDXHLXSMPQSN-UHFFFAOYSA-N
SMILES: CC(N1CCN(CC1)C2=CC=C(C=C2)CN(S(=O)(CC3=CC=CC=C3)=O)C4CCC4)=O
Biological Activity: RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist with the IC50 of 46 nM. Targeting the nuclear receptor RORγt is effective in autoimmune disorders[1].
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RORγt inverse agonist 30 | RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist with the IC50 of 46 nM. Targeting the nuclear receptor RORγt is effective in autoimmune disorders. | |||||||||||||||||||||
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References
Keywords
