1448525-91-4
Chemical Structure
S55746 hydrochloride
Synonym(s): BCL201 hydrochloride
- CAS No.: 1448525-91-4
- Formula:C43H43ClN4O6
- Molecular Weight:747.28
IUPAC Name: (S)-N-(4-hydroxyphenyl)-3-(6-(3-(morpholinomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)benzo[d][1,3]dioxol-5-yl)-N-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide hydrochloride
InChIKey: RAUZIGXCAJHBEL-WAQYZQTGSA-N
SMILES: O=C(C1=C2CCCCN2C(C3=C(C(N4CC5=C(C=CC=C5)C[C@H]4CN6CCOCC6)=O)C=C(OCO7)C7=C3)=C1)N(C8=CC=C(O)C=C8)C9=CC=CC=C9.Cl
Biological Activity: S55746 hydrochloride (BCL201 hydrochloride) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 hydrochloride (BCL201 hydrochloride) has antitumor activity with low toxicity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
S55746 hydrochloride | 98.83% | S55746 hydrochloride (BCL201 hydrochloride) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 hydrochloride (BCL201 hydrochloride) has antitumor activity with low toxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.99
HY-117288S55746 -
Similarity Score 0.67
HY-138697BS65487 hydrochloride -
Similarity Score 0.67
HY-138697S65487 -
Similarity Score 0.65
HY-138697AS65487 sulfate -
Similarity Score 0.65
HY-168983Lonitoclax -
Similarity Score 0.47
HY-154984JET-209 -
Similarity Score 0.46
HY-159905HPK1-IN-54 -
Similarity Score 0.46
HY-18351AIndotecan hydrochloride -
Similarity Score 0.45
HY-162651PROTAC BRD9 Degrader-8 -
Explore the MedChemAI to find more analogs