1452459-50-5
Chemical Structure
FPI-1523
- CAS No.: 1452459-50-5
- Formula:C9H14N4O7S
- Molecular Weight:322.30
IUPAC Name: (1R,2S,5R)-2-(2-acetylhydrazine-1-carbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate
InChIKey: WVZOCYGRXONJLX-RQJHMYQMSA-N
SMILES: CC(NNC([C@H]1[N@@]2C(N([C@H](CC1)C2)OS(=O)(O)=O)=O)=O)=O
Biological Activity: FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity[1].
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FPI-1523 | FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity. | |||||||||||||||||||||
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Keywords