148245-83-4
148245-83-4
Chemical Structure
Saussureamine C
- CAS No.: 148245-83-4
- Formula:C19H26N2O5
- Molecular Weight:362.42
IUPAC Name: (((3R,3aS,6aR,9aR,9bS)-6,9-dimethylene-2-oxododecahydroazuleno[4,5-b]furan-3-yl)methyl)-L-asparagine
InChIKey: MZFVEYVQALPRDY-HHHJXDIYSA-N
SMILES: O=C(N)C[C@@H](C(O)=O)NC[C@H]1[C@@](CC2)([H])[C@]([C@@]3([H])C(CC[C@@]3([H])C2=C)=C)([H])OC1=O
Biological Activity: Saussureamine C shows gastroprotective effect on acidified ethanol-induced gastric mucosal lesions in rats. Saussureamine C inhibits H274Y and N294S mutants and can be used for research of influenza virus infection. Saussureamine C can be isolated from the dried roots of Saussurea lappa Clarke[1][2].
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Saussureamine C | Saussureamine C shows gastroprotective effect on acidified ethanol-induced gastric mucosal lesions in rats. Saussureamine C inhibits H274Y and N294S mutants and can be used for research of influenza virus infection. Saussureamine C can be isolated from the dried roots of Saussurea lappa Clarke. | |||||||||||||||||||||
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References
- [1]. Yoshikawa M, et al. Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix. Chem Pharm Bull (Tokyo). 1993 Jan;41(1):214-6. [Content Brief]
- [2]. Tou WI, et al. Residue-based design of small molecule inhibitor for H1N1, H5N1 and H7N1 mutants. J Mol Model. 2016 Jan;22(1):4. [Content Brief]
