Saussureamine C
Saussureamine C shows gastroprotective effect on acidified ethanol-induced gastric mucosal lesions in rats. Saussureamine C inhibits H274Y and N294S mutants and can be used for research of influenza virus infection. Saussureamine C can be isolated from the dried roots of Saussurea lappa Clarke.
For research use only. We do not sell to patients.
- CAS No.: 148245-83-4
- Formula: C19H26N2O5
- Molecular Weight:362.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Macrophage | IC50 |
16 μg/mL
Compound: 12
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Antiinflammatory activity in mouse macrophages assessed as LPS-induced nitric oxide production
Antiinflammatory activity in mouse macrophages assessed as LPS-induced nitric oxide production
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10.1039/C2MD20172K |
Chemical Information
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CAS No. 148245-83-4
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Molecular Weight 362.42
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Formula C19H26N2O5
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SMILES
O=C(N)C[C@@H](C(O)=O)NC[C@H]1[C@@](CC2)([H])[C@]([C@@]3([H])C(CC[C@@]3([H])C2=C)=C)([H])OC1=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yoshikawa M, et al. Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix. Chem Pharm Bull (Tokyo). 1993 Jan;41(1):214-6. [Content Brief]
[2]. Tou WI, et al. Residue-based design of small molecule inhibitor for H1N1, H5N1 and H7N1 mutants. J Mol Model. 2016 Jan;22(1):4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Saussureamine C Related Classifications
HY-125540 Related Classifications
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