15015-57-3
Chemical Structure
LasR antagonist-2
- CAS No.: 15015-57-3
- Formula:C12H10O2S2
- Molecular Weight:250.34
IUPAC Name: 4,4'-disulfanediyldiphenol
InChIKey: XGKGITBBMXTKTE-UHFFFAOYSA-N
SMILES: OC(C=C1)=CC=C1SSC2=CC=C(O)C=C2
Biological Activity: LasR antagonist-2 is a LasR competitive antagonist and quorum sensing inhibitor, with a Kd value of 7.04 μM against LasR of Pseudomonas aeruginosa. LasR antagonist-2 reduces the production of virulence factors including elastase (elastase), pyocyanin (pyocyanin) and rhamnolipid (rhamnolipid). LasR antagonist-2 inhibits bacterial (bacterial) swarming and swimming motility, and moderately suppresses biofilm formation. LasR antagonist-2 inhibits Pseudomonas aeruginosa infection in the greater wax moth larva model. Elastase-IN-3 can be used in studies related to Pseudomonas aeruginosa infection[1].
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LasR antagonist-2 | 99.69% | LasR antagonist-2 is a LasR competitive antagonist and quorum sensing inhibitor, with a Kd value of 7.04 μM against LasR of Pseudomonas aeruginosa. LasR antagonist-2 reduces the production of virulence factors including elastase (elastase), pyocyanin (pyocyanin) and rhamnolipid (rhamnolipid). LasR antagonist-2 inhibits bacterial (bacterial) swarming and swimming motility, and moderately suppresses biofilm formation. LasR antagonist-2 inhibits Pseudomonas aeruginosa infection in the greater wax moth larva model. Elastase-IN-3 can be used in studies related to Pseudomonas aeruginosa infection. | ||||||||||||||||||||
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Keywords
