154189-24-9
Chemical Structure
Sibenadet hydrochloride
Synonym(s): AR-C68397AA
- CAS No.: 154189-24-9
- Formula:C22H29ClN2O5S2
- Molecular Weight:501.06
IUPAC Name: 4-hydroxy-7-(2-((2-((3-phenethoxypropyl)sulfonyl)ethyl)amino)ethyl)benzo[d]thiazol-2(3H)-one hydrochloride
InChIKey: YXOKBHUPEBNZOG-UHFFFAOYSA-N
SMILES: O=C1SC2=C(C=CC(O)=C2N1)CCNCCS(=O)(CCCOCCC3=CC=CC=C3)=O.[H]Cl
Biological Activity: Sibenadet hydrochloride (AR-C68397AA) is a dual D2 dopamine receptor, beta2-adrenoceptor agonist with bronchodilator activity. Investigation in animal models of key chronic obstructive pulmonary disease (COPD) symptoms has demonstrated that Sibenadet hydrochloride effectively inhibits sensory nerve activity, thereby reducing reflex cough, mucus production and tachypnoea.
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Sibenadet hydrochloride | Sibenadet hydrochloride (AR-C68397AA) is a dual D2 dopamine receptor, beta2-adrenoceptor agonist with bronchodilator activity. Investigation in animal models of key chronic obstructive pulmonary disease (COPD) symptoms has demonstrated that Sibenadet hydrochloride effectively inhibits sensory nerve activity, thereby reducing reflex cough, mucus production and tachypnoea. | |||||||||||||||||||||
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Keywords