155114-38-8
155114-38-8
Chemical Structure
Gypsetin
- CAS No.: 155114-38-8
- Formula:C32H36N4O4
- Molecular Weight:540.65
InChIKey: CXDDBHFLLPBKRS-OVYULKEKSA-N
SMILES: C=CC(C)([C@]12[C@](C3=CC=CC=C3N1)(C[C@]4([H])N2C([C@@]5([H])N([C@@]6([C@](C5)(C7=CC=CC=C7N6)O)C(C)(C)C=C)C4=O)=O)O)C
Biological Activity: Gypsetin can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with an IC50 of 18 μM, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μM. Gypsetin also inhibits Oleic acid from forming cholesterol esters with an IC50 of 0.65 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Gypsetin | Gypsetin can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with an IC50 of 18 μM, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μM. Gypsetin also inhibits Oleic acid from forming cholesterol esters with an IC50 of 0.65 μM. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
