1601-18-9
1601-18-9
Chemical Structure
Indomethacin methylester
Synonym(s): Indometacin methylester
- CAS No.: 1601-18-9
- Formula:C20H18ClNO4
- Molecular Weight:371.81
IUPAC Name: methyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
InChIKey: OKHORWCUMZIORR-UHFFFAOYSA-N
SMILES: O=C(CC1=C(C)N(C(C2=CC=C(C=C2)Cl)=O)C3=C1C=C(C=C3)OC)OC
Biological Activity: Indomethacin methylester (Compound 10; Indometacin methylester) is a potent and selective AKR1C3 inhibitor with an IC50 value of 5.67 μM. Indomethacin methylester is promising for research of postate cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Indomethacin methylester | 99.92% | Indomethacin methylester (Compound 10; Indometacin methylester) is a potent and selective AKR1C3 inhibitor with an IC50 value of 5.67 μM. Indomethacin methylester is promising for research of postate cancer. | ||||||||||||||||||||
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Indomethacin-d4 Methyl Ester | 98.38% | Indomethacin-d4 Methyl Ester is the deuterium labeled Indomethacin. Indomethacin (Indometacin) is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells. Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes. | ||||||||||||||||||||
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