1607589-56-9
Chemical Structure
NMDA receptor antagonist 4
- CAS No.: 1607589-56-9
- Formula:C15H18FN
- Molecular Weight:231.31
IUPAC Name: 9-fluoro-5,6,8,9,10,11-hexahydro-7H-5,9:7,11-dimethanobenzo[9]annulen-7-amine
InChIKey: JTJHHYKAFPPPFM-UHFFFAOYSA-N
SMILES: NC12CC3C4=CC=CC=C4C(CC(F)(C2)C3)C1
Biological Activity: NMDA receptor antagonist 4 (IIc) is a uncompetitive, voltage-dependent, orally active NMDAR blocker, with an IC50 of 1.93 μM. NMDA receptor antagonist 4 shows a positive predicted blood-brain-barrier (BBB) permeability, and can be studied in Alzheimer's disease[1].
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NMDA receptor antagonist 4 | 99.64% | NMDA receptor antagonist 4 (IIc) is a uncompetitive, voltage-dependent, orally active NMDAR blocker, with an IC50 of 1.93 μM. NMDA receptor antagonist 4 shows a positive predicted blood-brain-barrier (BBB) permeability, and can be studied in Alzheimer's disease. | ||||||||||||||||||||
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Keywords