1609258-91-4
1609258-91-4
Chemical Structure
PF2562
- CAS 番号: 1609258-91-4
- Formula:C19H17N5O
- Molecular Weight:331.37
IUPAC Name: 4-(4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy)-1H-pyrazolo[4,3-c]pyridine
InChIKey: IDIUJOHYYBNCPC-UHFFFAOYSA-N
SMILES: CC1=CC(OC2=NC=CC3=C2C=NN3)=CC=C1C4=C(N=CN=C4C)C
Biological Activity: PF2562 (Example 6), a dopamine D1 ligand, ascts as a dopamine D1 agonist or partial agonist. PF2562 binds to human D1 receptor with a Ki of 113 nM. PF2562 exhibits activity against human D1 cAMP with an EC50 of 568 nM in HTRF assay[1].
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PF2562 | PF2562 (Example 6), a dopamine D1 ligand, ascts as a dopamine D1 agonist or partial agonist. PF2562 binds to human D1 receptor with a Ki of 113 nM. PF2562 exhibits activity against human D1 cAMP with an EC50 of 568 nM in HTRF assay. | |||||||||||||||||||||
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References
Keywords
