1621585-22-5
1621585-22-5
Chemical Structure
PF-06663195
- CAS No.: 1621585-22-5
- Formula:C18H18F3N3O2S
- Molecular Weight:397.41
IUPAC Name: (4S,4aR,6R,8aS)-8a-(2,4-difluorophenyl)-4-(fluoromethyl)-6-(3-methylisoxazol-5-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine
InChIKey: JIAYOIBUKDISBO-IYPIGGPWSA-N
SMILES: FC[C@@H]1[C@@]2([H])[C@](N=C(S1)N)(C3=C(C=C(C=C3)F)F)CO[C@@H](C4=CC(C)=NO4)C2
Biological Activity: PF-06663195 is a β-secretase (BACE1) inhibitor, with BACE1 CFA and BACE1 WCA IC50 values of 53 and 15 nM, respectively. PF-06663195 can be used for Alzheimer's disease research[1].
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PF-06663195 | PF-06663195 is a β-secretase (BACE1) inhibitor, with BACE1 CFA and BACE1 WCA IC50 values of 53 and 15 nM, respectively. PF-06663195 can be used for Alzheimer's disease research. | |||||||||||||||||||||
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References
Keywords
