1629138-41-5
1629138-41-5
Chemical Structure
SRI-011381
- CAS No.: 1629138-41-5
- Formula:C20H31N3O
- Molecular Weight:329.48
IUPAC Name: 1-benzyl-3-cyclohexyl-1-(piperidin-4-ylmethyl)urea
InChIKey: LNOPAJNGRAPFKZ-UHFFFAOYSA-N
SMILES: O=C(NC1CCCCC1)N(CC2=CC=CC=C2)CC3CCNCC3
Biological Activity: SRI-011381 is an orally active TGF-β signaling agonist, exhibits neuroprotective effects[1][2].
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SRI-011381 | 99.40% | SRI-011381 is an orally active TGF-β signaling agonist, exhibits neuroprotective effects. | ||||||||||||||||||||
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SRI-011381 (Standard) | ≥98% | SRI-011381 (Standard) is the analytical standard of SRI-011381 (HY-100347). This product is intended for research and analytical applications. SRI-011381 is an orally active TGF-β signaling agonist, exhibits neuroprotective effects. | ||||||||||||||||||||
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SRI-011381-d5 | SRI-011381-d5 is the deuterium labeled SRI-011381 (HY-100347). SRI-011381 is an orally active TGF-β signaling agonist, exhibits neuroprotective effects. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-100347ASRI-011381 hydrochloride -
Similarity Score 0.65
HY-W046404Benzyl (piperidin-4-ylmethyl)carbamate -
Similarity Score 0.63
HY-19370FPS-ZM1 -
Similarity Score 0.61
HY-B0682Mitiglinide -
Similarity Score 0.61
HY-B2048RPencycuron (Standard) -
Similarity Score 0.61
![3-Benzyl-3,9-diazaspiro[5.5]undecane Chemical Structure](//file.medchemexpress.com/product_pic/hy-30534.gif)
HY-305343-Benzyl-3,9-diazaspiro[5.5]undecane -
Similarity Score 0.61
HY-146370COX-2-IN-12 -
Similarity Score 0.60
![trans-4-[Bis(phenylmethyl)amino]cyclohexanecarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-z0691.gif)
HY-Z0691trans-4-[Bis(phenylmethyl)amino]cyclohexanecarboxylic acid -
Similarity Score 0.60
![7-Benzyl-2,7-diazaspiro[3.5]nonane dihydrochloride Chemical Structure](//file.medchemexpress.com/product_pic/hy-30761a.gif)
HY-30761A7-Benzyl-2,7-diazaspiro[3.5]nonane dihydrochloride -
Explore the MedChemAI to find more analogs
![3-Benzyl-3,9-diazaspiro[5.5]undecane Chemical Structure](http://file.medchemexpress.com/product_pic/hy-30534.gif)
![trans-4-[Bis(phenylmethyl)amino]cyclohexanecarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-z0691.gif)
![7-Benzyl-2,7-diazaspiro[3.5]nonane dihydrochloride Chemical Structure](http://file.medchemexpress.com/product_pic/hy-30761a.gif)
References
- [1]. Jingyin Han, et al. The Improvement Effect of Sodium Ferulate on the Formation of Pulmonary Fibrosis in Silicosis Mice Through the Neutrophil Alkaline Phosphatase 3 (NALP3)/Transforming Growth Factor-β1 (TGF-β1)/α-Smooth Muscle Actin (α-SMA) Pathway. Med Sci Monit. 2021 Jun 15;27:e927978. [Content Brief]
- [2]. Qian Wu, et al. Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-β signaling. Theranostics. 2021 Jul 25;11(17):8480-8499. [Content Brief]
