1630763-23-3
Chemical Structure
CIGB-552
- CAS No.: 1630763-23-3
- Formula:C131H198N38O24
- Molecular Weight:2689.21
SMILES: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CCCCN)C(NCC(N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(O)=O)CC2=CNC3=CC=CC=C23)=O)CC4=CC=CC=C4)=O)=O)=O)=O)NC([C@H](CCCCN)NC([C@@H](NC([C@H](CCCCN)NC([C@@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H]([C@H](O)C)NC([C@@H]5N(CCC5)C([C@H](CCCCN)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@@H](NC(C)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)=O)=O)=O)CC8=CNC9=CC=CC=C89)=O)=O
Biological Activity: CIGB-552 is a cell-penetrating peptide with anti-tumor properties with the IC50 of 23 μM in H460 cells. CIGB-552 can increase the level of protein COMMD1. CIGB-552 significantly inhibits the NF-κB signaling pathway. CIGB-552 can promote apoptosis of the tumor cells. CIGB-552 can induce the accumulation of reactive oxygen species (ROS) in tumor cells. CIGB-552 has anti-inflammatory and anti-angiogenic effects. CIGB-552 can be used for the research of the lung cancer and colon cancer[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CIGB-552 | 98.66% | CIGB-552 is a cell-penetrating peptide with anti-tumor properties with the IC50 of 23 μM in H460 cells. CIGB-552 can increase the level of protein COMMD1. CIGB-552 significantly inhibits the NF-κB signaling pathway. CIGB-552 can promote apoptosis of the tumor cells. CIGB-552 can induce the accumulation of reactive oxygen species (ROS) in tumor cells. CIGB-552 has anti-inflammatory and anti-angiogenic effects. CIGB-552 can be used for the research of the lung cancer and colon cancer. | ||||||||||||||||||||
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