169764-95-8
Chemical Structure
TCB-32 hydrochloride
- CAS No.: 169764-95-8
- Formula:C32H44Cl4N18O2
- Molecular Weight:854.62
InChIKey: HOAILXQYXRIUKU-XVTAPYCBSA-N
SMILES: O=C(C1=CC=CC(C(NC2=CC(/C(C)=N/NC(N)=N)=CC(/C(C)=N/NC(N)=N)=C2)=O)=C1)NC3=CC(/C(C)=N/NC(N)=N)=CC(/C(C)=N/NC(N)=N)=C3.Cl.Cl.Cl.Cl
Biological Activity: TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC50 of 0.88 μM. TCB-32 hydrochloride significantly increases cell proliferation through activating FGFR1 signaling pathway as bFGF and its downstream ERK1/2 with excellent thermal stability. TCB-32 hydrochloride can replace bFGF in serum-free cell culture media. TCB-32 hydrochloride can be used for tissue repair and wound healing related diseases like psoriasis and eczema research[1][2].
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TCB-32 hydrochloride | 97.69% | TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC50 of 0.88 μM. TCB-32 hydrochloride significantly increases cell proliferation through activating FGFR1 signaling pathway as bFGF and its downstream ERK1/2 with excellent thermal stability. TCB-32 hydrochloride can replace bFGF in serum-free cell culture media. TCB-32 hydrochloride can be used for tissue repair and wound healing related diseases like psoriasis and eczema research. | ||||||||||||||||||||
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Keywords
