TCB-32 hydrochloride
Based on 1 Customer Validation
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC50 of 0.88 μM. TCB-32 hydrochloride significantly increases cell proliferation through activating FGFR1 signaling pathway as bFGF and its downstream ERK1/2 with excellent thermal stability. TCB-32 hydrochloride can replace bFGF in serum-free cell culture media. TCB-32 hydrochloride can be used for tissue repair and wound healing related diseases like psoriasis and eczema research.
For research use only. We do not sell to patients.
- Purity: 97.69%
- CAS No.: 169764-95-8
- Formula: C32H44Cl4N18O2
- Molecular Weight:854.62
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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FGFR1 0.88 μM (EC50) |
ERK1 |
ERK2 |
Chemical Information
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CAS No. 169764-95-8
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Appearance Solid
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Molecular Weight 854.62
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Formula C32H44Cl4N18O2
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Color White to off-white
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SMILES
O=C(C1=CC=CC(C(NC2=CC(/C(C)=N/NC(N)=N)=CC(/C(C)=N/NC(N)=N)=C2)=O)=C1)NC3=CC(/C(C)=N/NC(N)=N)=CC(/C(C)=N/NC(N)=N)=C3.Cl.Cl.Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (117.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1701 mL | 5.8506 mL | 11.7011 mL | 29.2528 mL |
| 5 mM | 0.2340 mL | 1.1701 mL | 2.3402 mL | 5.8506 mL | |
| 10 mM | 0.1170 mL | 0.5851 mL | 1.1701 mL | 2.9253 mL | |
| 15 mM | 0.0780 mL | 0.3900 mL | 0.7801 mL | 1.9502 mL | |
| 20 mM | 0.0585 mL | 0.2925 mL | 0.5851 mL | 1.4626 mL | |
| 25 mM | 0.0468 mL | 0.2340 mL | 0.4680 mL | 1.1701 mL | |
| 30 mM | 0.0390 mL | 0.1950 mL | 0.3900 mL | 0.9751 mL | |
| 40 mM | 0.0293 mL | 0.1463 mL | 0.2925 mL | 0.7313 mL | |
| 50 mM | 0.0234 mL | 0.1170 mL | 0.2340 mL | 0.5851 mL | |
| 60 mM | 0.0195 mL | 0.0975 mL | 0.1950 mL | 0.4875 mL | |
| 80 mM | 0.0146 mL | 0.0731 mL | 0.1463 mL | 0.3657 mL | |
| 100 mM | 0.0117 mL | 0.0585 mL | 0.1170 mL | 0.2925 mL |
TCB-32 hydrochloride Related Classifications
HY-176862A Related Classifications
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