175463-14-6
Chemical Structure
Gemifloxacin
Synonym(s): SB-265805; LB20304
- CAS No.: 175463-14-6
- Formula:C18H20FN5O4
- Molecular Weight:389.38
IUPAC Name: (Z)-7-(3-(aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
InChIKey: ZRCVYEYHRGVLOC-HYARGMPZSA-N
SMILES: NCC(C1)/C(CN1C(N=C2C(C(C(C(O)=O)=CN2C3CC3)=O)=C4)=C4F)=N/OC
Biological Activity: Gemifloxacin, a fluoroquinolone, is a potent and orally active antipneumococcal agent. Gemifloxacin shows bactericidal activity against highly quinolone-resistant pneumococci.Gemifloxacin can be used for the research of respiratory infections, such as community-acquired pneumonia (CAP) and acute exacerbation of chronic bronchitis (AECB)[1][2].
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Gemifloxacin | Gemifloxacin, a fluoroquinolone, is a potent and orally active antipneumococcal agent. Gemifloxacin shows bactericidal activity against highly quinolone-resistant pneumococci.Gemifloxacin can be used for the research of respiratory infections, such as community-acquired pneumonia (CAP) and acute exacerbation of chronic bronchitis (AECB). | |||||||||||||||||||||
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- [1]. Yoo BK, et al. Gemifloxacin: a new fluoroquinolone approved for treatment of respiratory infections. Ann Pharmacother. 2004 Jul-Aug;38(7-8):1226-35. [Content Brief]
- [2]. Davies TA, et al. Antipneumococcal activities of gemifloxacin compared to those of nine other agents. Antimicrob Agents Chemother. 2000 Feb;44(2):304-10. [Content Brief]
Keywords