178803-51-5
178803-51-5
Chemical Structure
SNC162
- CAS No.: 178803-51-5
- Formula:C27H37N3O
- Molecular Weight:419.60
IUPAC Name: 4-((S)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(phenyl)methyl)-N,N-diethylbenzamide
InChIKey: WGIDFDFAOQVAHY-UFPGJGBJSA-N
SMILES: C[C@@H](CN([C@@H](C1)C)CC=C)N1[C@@H](C2=CC=CC=C2)C3=CC=C(C=C3)C(N(CC)CC)=O
Biological Activity: SNC162 is a delta-opioid receptor agonist with an IC50 of 0.94 nM. SNC162 has antidepressant-like and antinociceptiv effects[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SNC162 | 99.72% | SNC162 is a delta-opioid receptor agonist with an IC50 of 0.94 nM. SNC162 has antidepressant-like and antinociceptiv effects. | ||||||||||||||||||||
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References
- [1]. Jutkiewicz EM, et al. Delta-opioid agonists: differential efficacy and potency of SNC80, its 3-OH (SNC86) and 3-desoxy (SNC162) derivatives in Sprague-Dawley rats. J Pharmacol Exp Ther. 2004 Apr;309(1):173-81. [Content Brief]
- [2]. Banks ML, et al. Selective enhancement of fentanyl-induced antinociception by the delta agonist SNC162 but not by ketamine in rhesus monkeys: Further evidence supportive of delta agonists as candidate adjuncts to mu opioid analgesics. Pharmacol Biochem Behav. 2010 Dec;97(2):205-12. [Content Brief]
Keywords
