1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. Aligeron

Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.

For research use only. We do not sell to patients.

Aligeron Chemical Structure

Aligeron Chemical Structure

CAS No. : 70713-45-0

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Description

Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.

In Vitro

Aligeron shows a broad spectrum of antagonistic action against different spasmogens in different isolated organs. The experiments on isolated perfused rabbit artery shows the antagonistic action of aligeron against the vasoconstrictor effects of noradrenaline and adrenaline[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

In hypoventilation hypoxia, aligeron (5 mg/kg i.v.) and cinnarizine increase cortical resistance to hypoxia and accelerated the recovery of cortical bioelectrical activity. In KCl- and AMP-induced depressions aligeron shows a protective effect manifested in a decrease of the degree and duration of the depression[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

292.42

Formula

C20H24N2

CAS No.
SMILES

C=CCN1CCN(C(C2=CC=CC=C2)C3=CC=CC=C3)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Aligeron
Cat. No.:
HY-101602
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