1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. Aligeron

Aligeron 

Cat. No.: HY-101602
Handling Instructions

Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.

For research use only. We do not sell to patients.

Aligeron Chemical Structure

Aligeron Chemical Structure

CAS No. : 70713-45-0

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Description

Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.

In Vitro

Aligeron shows a broad spectrum of antagonistic action against different spasmogens in different isolated organs. The experiments on isolated perfused rabbit artery shows the antagonistic action of aligeron against the vasoconstrictor effects of noradrenaline and adrenaline[1]. The effect of aligeron in vitro lacks selectivity and is probably due to interference with the action of Ca2+[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

In hypoventilation hypoxia, aligeron (5 mg/kg i.v.) and cinnarizine increase cortical resistance to hypoxia and accelerated the recovery of cortical bioelectrical activity. In KCl- and AMP-induced depressions aligeron shows a protective effect manifested in a decrease of the degree and duration of the depression[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

292.42

Formula

C₂₀H₂₄N₂

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Aligeron
Cat. No.:
HY-101602
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