178928-68-2
Chemical Structure
NGD94-1
- CAS No.: 178928-68-2
- Formula:C18H20N6
- Molecular Weight:320.39
IUPAC Name: 2-(4-((2-phenyl-1H-imidazol-5-yl)methyl)piperazin-1-yl)pyrimidine
InChIKey: OTVQCHUIPJYASM-UHFFFAOYSA-N
SMILES: C1(N2CCN(CC3=CN=C(C4=CC=CC=C4)N3)CC2)=NC=CC=N1
Biological Activity: NGD94-1 is a potent and selective dopamine D4 receptor antagonist. NGD94-1 shows high affinity for the cloned human D4.2 receptor (Ki = 3.6 nM). NGD94-1 modulates the cognitive functions of the frontostriatal system and regulates dopaminergic transmission in Phencyclidine (PCP)-induced monkeys. NGD94-1 can be used for neurological disease research[1][2].
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NGD94-1 | 99.79% | NGD94-1 is a potent and selective dopamine D4 receptor antagonist. NGD94-1 shows high affinity for the cloned human D4.2 receptor (Ki = 3.6 nM). NGD94-1 modulates the cognitive functions of the frontostriatal system and regulates dopaminergic transmission in Phencyclidine (PCP)-induced monkeys. NGD94-1 can be used for neurological disease research. | ||||||||||||||||||||
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Keywords
