17968-82-0
17968-82-0
Chemical Structure
Prostaglandin D1
Synonym(s): PGD1
- CAS No.: 17968-82-0
- Formula:C20H34O5
- Molecular Weight:354.48
IUPAC Name: 7-((1R,2R,5S)-5-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-3-oxocyclopentyl)heptanoic acid
InChIKey: CIMMACURCPXICP-PNQRDDRVSA-N
SMILES: OC(CCCCCC[C@@H]1[C@H](C(C[C@@H]1O)=O)/C=C/[C@@H](O)CCCCC)=O
Biological Activity: Prostaglandin D1 is a prostanoid which causes contractile and relaxant on isolated human pial arteries, it is also an inhibitor of ADP-induced platelet aggregation with an IC50 value of 320 ng/ml. Prostaglandin D1 can be used for metabolic research[1][2].
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Prostaglandin D1 | 98.8% | Prostaglandin D1 is a prostanoid which causes contractile and relaxant on isolated human pial arteries, it is also an inhibitor of ADP-induced platelet aggregation with an IC50 value of 320 ng/ml. Prostaglandin D1 can be used for metabolic research. | ||||||||||||||||||||
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Prostaglandin D1-d4 | Prostaglandin D1-d4 (PGD1-d4) is deuterium labeled Prostaglandin D1. Prostaglandin D1 is a prostanoid which causes contractile and relaxant on isolated human pial arteries, it is also an inhibitor of ADP-induced platelet aggregation with an IC50 value of 320 ng/ml. Prostaglandin D1 can be used for metabolic research. | |||||||||||||||||||||
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References
- [1]. Bundy GL, et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J Med Chem. 1983 Jun;26(6):790-9. [Content Brief]
- [2]. Uski TK, et al. Characterization of the prostanoid receptors and of the contractile effects of prostaglandin F2 alpha in human pial arteries. Acta Physiol Scand. 1984 Aug;121(4):369-78. [Content Brief]
Keywords
