1807780-00-2
Chemical Structure
EP2 receptor agonist 2
- CAS No.: 1807780-00-2
- Formula:C19H21NO5S
- Molecular Weight:375.44
IUPAC Name: 2-((2R,4aR,5S,6R,7aS)-6-hydroxy-5-(phenoxymethyl)octahydrocyclopenta[b]pyran-2-yl)thiazole-4-carboxylic acid
InChIKey: OLIHKSYTBDCPSM-HSMRXVHUSA-N
SMILES: OC(C1=CSC([C@@H](CC2)O[C@](C[C@H]3O)([H])[C@@]2([H])[C@H]3COC4=CC=CC=C4)=N1)=O
Biological Activity: EP2 receptor agonist 2 (compound 18a) is a potent and selective G protein-biased EP2 receptor agonist (hEP2G protein EC50 = 13 nM, hEP2β arrestin EC50 > 10000 nM). EP2 receptor agonist 2 exhibits excellent selectivity over hEP1/3/4, hIP and hFP (EC50s > 10000 nM)[1].
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EP2 receptor agonist 2 | EP2 receptor agonist 2 (compound 18a) is a potent and selective G protein-biased EP2 receptor agonist (hEP2G protein EC50 = 13 nM, hEP2β arrestin EC50 > 10000 nM). EP2 receptor agonist 2 exhibits excellent selectivity over hEP1/3/4, hIP and hFP (EC50s > 10000 nM). | |||||||||||||||||||||
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Keywords
