1811548-74-9
1811548-74-9
Chemical Structure
Antitumor agent-44
- CAS No.: 1811548-74-9
- Formula:C24H15N3O3
- Molecular Weight:393.39
IUPAC Name: benzo[d][1,3]dioxol-5-yl(9-(pyrimidin-2-yl)-9H-carbazol-1-yl)methanone
InChIKey: JNRQJBKOMNNIRT-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(OCO2)C2=C1)C3=CC=CC4=C3N(C5=NC=CC=N5)C6=C4C=CC=C6
Biological Activity: Antitumor agent-44 (Compound 5n) disrupts the mitochondrial homeostasis, induces cell cycle arrest and apoptosis in human adenocarcinoma cells. Antitumor agent-44 (Compound 5n) possesses good anti-tumor activity in a lung-cancer-cell xenograft mice model[1].
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Antitumor agent-44 | Antitumor agent-44 (Compound 5n) disrupts the mitochondrial homeostasis, induces cell cycle arrest and apoptosis in human adenocarcinoma cells. Antitumor agent-44 (Compound 5n) possesses good anti-tumor activity in a lung-cancer-cell xenograft mice model. | |||||||||||||||||||||
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