Antitumor agent-44
Antitumor agent-44 (Compound 5n) disrupts the mitochondrial homeostasis, induces cell cycle arrest and apoptosis in human adenocarcinoma cells. Antitumor agent-44 (Compound 5n) possesses good anti-tumor activity in a lung-cancer-cell xenograft mice model.
For research use only. We do not sell to patients.
- CAS No.: 1811548-74-9
- Formula: C24H15N3O3
- Molecular Weight:393.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.82 μM
Compound: 5n
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Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
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[PMID: 35219149] |
| NRK-52E | IC50 |
1.25 μM
Compound: 5n
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Antiproliferative activity against rat NRK-52E cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
Antiproliferative activity against rat NRK-52E cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
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[PMID: 35219149] |
Chemical Information
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CAS No. 1811548-74-9
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Molecular Weight 393.39
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Formula C24H15N3O3
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SMILES
O=C(C1=CC=C(OCO2)C2=C1)C3=CC=CC4=C3N(C5=NC=CC=N5)C6=C4C=CC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitumor agent-44 Related Classifications
HY-144361 Related Classifications
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