1821669-43-5
1821669-43-5
Chemical Structure
BRD2492
- CAS No.: 1821669-43-5
- Formula:C20H18N4O2
- Molecular Weight:346.38
IUPAC Name: 4-acetamido-N-(2-amino-5-(pyridin-4-yl)phenyl)benzamide
InChIKey: BBHURYMVPMFILR-UHFFFAOYSA-N
SMILES: O=C(NC1=C(N)C=CC(C2=CC=NC=C2)=C1)C3=CC=C(NC(C)=O)C=C3
Biological Activity: BRD2492 (compound 6d) is a potent, selective HDAC1 and HDAC2 inhibitor with IC50s of 13.2 nM and 77.2 nM, respecrtively. BRD2492 exhibits >100-fold selectivity for HDAC1/2 over selectivity over HDAC3 and HDAC6. BRD2492 inhibits breast cancer cell lines growth with IC50s of 1.01 μM and 11.13 μM for T-47D and MCF-7 cells, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BRD2492 | 99.22% | BRD2492 (compound 6d) is a potent, selective HDAC1 and HDAC2 inhibitor with IC50s of 13.2 nM and 77.2 nM, respecrtively. BRD2492 exhibits >100-fold selectivity for HDAC1/2 over selectivity over HDAC3 and HDAC6. BRD2492 inhibits breast cancer cell lines growth with IC50s of 1.01 μM and 11.13 μM for T-47D and MCF-7 cells, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
