185341-71-3
185341-71-3
Chemical Structure
8-Chloro-ATP
- CAS No.: 185341-71-3
- Formula:C10H15ClN5O13P3
- Molecular Weight:541.63
IUPAC Name: (((2R,3S,4R,5R)-5-(6-amino-8-chloro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid
InChIKey: NXKRKKQPDYYKFT-UUOKFMHZSA-N
SMILES: NC1=NC=NC2=C1N=C(Cl)N2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O3
Biological Activity: 8-Chloro-ATP, an ATP (HY-B2176) analog, is a topoisomerase II (Topo II) inhibitor. 8-Chloro-ATP inhibits DNA synthesis and induces DNA double-stranded breaks (DSBs). 8-Chloro-ATP inhibits Topo II-catalyzed ATP hydrolysis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
8-Chloro-ATP | 8-Chloro-ATP, an ATP (HY-B2176) analog, is a topoisomerase II (Topo II) inhibitor. 8-Chloro-ATP inhibits DNA synthesis and induces DNA double-stranded breaks (DSBs). 8-Chloro-ATP inhibits Topo II-catalyzed ATP hydrolysis. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
