186086-10-2
Chemical Structure
HNS-32
- CAS No.: 186086-10-2
- Formula:C24H29N3
- Molecular Weight:359.51
IUPAC Name: (E)-5-isopropyl-N,N,3,8-tetramethyl-N'-(pyridin-2-ylmethyl)azulene-1-carboximidamide
InChIKey: VKDSEWRXCPKODE-SHHOIMCASA-N
SMILES: CC1=C2C(/C(N(C)C)=N\CC3=NC=CC=C3)=CC(C)=C2C=C(C(C)C)C=C1
Biological Activity: HNS-32 is a compound with antiarrhythmic and vasodilatory effects in canine hearts, showing superior protective effects against ischemic and reperfusion arrhythmias compared to an equivalent dose of Mexiletine hydrochloride (HY-A0093). Furthermore, HNS-32 exhibits significant negative chronotropic effects on mammalian ventricular myocardium, indicating its potential application value in the study of acute coronary syndrome[1].
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HNS-32 | HNS-32 is a compound with antiarrhythmic and vasodilatory effects in canine hearts, showing superior protective effects against ischemic and reperfusion arrhythmias compared to an equivalent dose of Mexiletine hydrochloride (HY-A0093). Furthermore, HNS-32 exhibits significant negative chronotropic effects on mammalian ventricular myocardium, indicating its potential application value in the study of acute coronary syndrome. | |||||||||||||||||||||
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Keywords
