1883598-69-3
1883598-69-3
Chemical Structure
IACS-9571 TFA
Synonym(s): ASIS-P040 TFA
- CAS. Nr.: 1883598-69-3
- Formula:C34H43F3N4O10S
- Molecular Weight:756.79
IUPAC Name: N-(6-(3-(4-(dimethylamino)butoxy)-5-propoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-3,4-dimethoxybenzenesulfonamide 2,2,2-trifluoroacetate
InChIKey: GAOCLDPTFLDJIP-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(OC)C(OC)=C1)(NC2=C(OC3=CC(OCCC)=CC(OCCCCN(C)C)=C3)C=C(N4C)C(N(C)C4=O)=C2)=O.FC(F)(C(O)=O)F
Biological Activity: IACS-9571 (trifluoroacetate) is a potent and selective inhibitor of TRIM24 and BRPF1, with IC50 of 8 nM for TRIM24, and Kd of 31 nM and 14 nM for TRIM24 and BRPF1, respectively.
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IACS-9571 TFA | IACS-9571 (trifluoroacetate) is a potent and selective inhibitor of TRIM24 and BRPF1, with IC50 of 8 nM for TRIM24, and Kd of 31 nM and 14 nM for TRIM24 and BRPF1, respectively. | |||||||||||||||||||||
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