1917294-46-2
1917294-46-2
Chemical Structure
PF-04745637
- CAS No.: 1917294-46-2
- Formula:C27H32ClF3N2O2
- Molecular Weight:509.00
IUPAC Name: 1-(4-chlorophenyl)-N-(2-(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)-3-phenylpropyl)cyclopentane-1-carboxamide
InChIKey: PAEBEJVPSADOMC-UHFFFAOYSA-N
SMILES: O=C(C1(C2=CC=C(Cl)C=C2)CCCC1)NCC(N3CCC(C(F)(F)F)(O)CC3)CC4=CC=CC=C4
Biological Activity: PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PF-04745637 | 99.60% | PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.51
HY-119595Haloperidide -
Similarity Score 0.50
HY-128038N-Desmethyl-loperamide -
Similarity Score 0.50
HY-B0418ALoperamide hydrochloride -
Similarity Score 0.50
HY-112488EXEL-0346 -
Similarity Score 0.50
HY-W700684N-Didesmethyl Loperamide -
Similarity Score 0.50
HY-156131Loperamide -
Similarity Score 0.49
HY-128038SN-Desmethyl-loperamide-d3 -
Similarity Score 0.49
HY-128132C3a receptor agonist 1 -
Similarity Score 0.48
HY-P1701Morphiceptin -
Explore the MedChemAI to find more analogs
