1919050-87-5
Chemical Structure
RL648_81
- CAS No.: 1919050-87-5
- Formula:C17H17F4N3O2
- Molecular Weight:371.33
IUPAC Name: ethyl (2-amino-3-fluoro-4-((4-(trifluoromethyl)benzyl)amino)phenyl)carbamate
InChIKey: MVSMZQRRMPUGHI-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C(F)=C1N)NCC2=CC=C(C=C2)C(F)(F)F)OCC
Biological Activity: RL648_81 is a specific KQT-like subfamily 2/3 (KCNQ2/3) activator with an EC50 of 190 nM. RL648_81 robustly shifts the V1/2 of KCNQ2/3 channels towards hyperpolarized potentials.RL648_81 does not shift the V1/2 of either KCNQ4 or KCNQ5.RL648_81 has?the?potential?for?neurologic disorders associated with neuronal hyperexcitability research[1].
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RL648_81 | 99.49% | RL648_81 is a specific KQT-like subfamily 2/3 (KCNQ2/3) activator with an EC50 of 190 nM. RL648_81 robustly shifts the V1/2 of KCNQ2/3 channels towards hyperpolarized potentials.RL648_81 does not shift the V1/2 of either KCNQ4 or KCNQ5.RL648_81 has?the?potential?for?neurologic disorders associated with neuronal hyperexcitability research. | ||||||||||||||||||||
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Keywords
