19388-87-5
19388-87-5
Chemical Structure
Taurolidine
- CAS No.: 19388-87-5
- Formula:C7H16N4O4S2
- Molecular Weight:284.36
IUPAC Name: 4,4'-methylenebis(1,2,4-thiadiazinane 1,1-dioxide)
InChIKey: AJKIRUJIDFJUKJ-UHFFFAOYSA-N
SMILES: O=S1(NCN(CN(CC2)CNS2(=O)=O)CC1)=O
Biological Activity: Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality[1][2].
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Taurolidine | 98.13% | Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality. | ||||||||||||||||||||
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Taurolidine (Standard) | 98.90% | Taurolidine (Standard) is the analytical standard of Taurolidine. This product is intended for research and analytical applications. Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality. | ||||||||||||||||||||
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Taurolidine-d6 | Taurolidine-d6 is the deuterium labeled Taurolidine (HY-W011522). Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.54
HY-D0875PIPES -
Similarity Score 0.53
HY-W011271PIPES monosodium -
Similarity Score 0.53
HY-148604Imuracetam -
Similarity Score 0.52
HY-W040147PIPES disodium -
Similarity Score 0.52
HY-108535RHEPES sodium (Standard) -
Similarity Score 0.52
HY-W327886PIPES dipotassium -
Similarity Score 0.52
HY-W342700PIPPS -
Similarity Score 0.52
HY-W717830CB-Cyclam -
Similarity Score 0.51
HY-W329824Spirazidine -
Explore the MedChemAI to find more analogs
References
- [1]. Marley K, et al. The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro. BMC Vet Res. 2013 Jan 18;9:15. doi: 10.1186/1746-6148-9-15. [Content Brief]
- [2]. Huang J, et al. Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2121244119. [Content Brief]
