195371-52-9

NSC 42834 Chemical Structure
195371-52-9

Chemical Structure

NSC 42834

Synonym(s): JAK2 Inhibitor V; Z3

  • CAS No.: 195371-52-9
  • Formula:C23H24N2O
  • Molecular Weight:344.45

IUPAC Name: 2-methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one

InChIKey: SETYDCSRABYHSW-UHFFFAOYSA-N

SMILES: O=C(C1=CC=CC=C1)C(CCC2=NC=CC=C2)(C)CCC3=NC=CC=C3

Biological Activity: NSC 42834 (JAK2 Inhibitor V), a novel specific inhibitor of Jak2, inhibits Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner but was not cytotoxic to cells at concentrations that inhibited kinase activity.

Cat. No. Product Name Purity Description Pricing
HY-15480 		NSC 42834 96.85% NSC 42834 (JAK2 Inhibitor V), a novel specific inhibitor of Jak2, inhibits Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner but was not cytotoxic to cells at concentrations that inhibited kinase activity.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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