199673-74-0
199673-74-0
Chemical Structure
LY334370 hydrochloride
- CAS No.: 199673-74-0
- Formula:C21H23ClFN3O
- Molecular Weight:387.88
IUPAC Name: 4-fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benzamide hydrochloride
InChIKey: DGPDGAPZTPSHBL-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C=C1)F)NC2=CC3=C(NC=C3C4CCN(CC4)C)C=C2.Cl
Biological Activity: LY334370 hydrochloride is a selective 5-HT1F receptor agonist with a Kd value of 0.446 nM. LY334370 hydrochlorid has anti-migraine activity[1][2].
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LY334370 hydrochloride | LY334370 hydrochloride is a selective 5-HT1F receptor agonist with a Kd value of 0.446 nM. LY334370 hydrochlorid has anti-migraine activity. | |||||||||||||||||||||
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References
- [1]. Wainscott DB, et al. [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties. Naunyn Schmiedebergs Arch Pharmacol. 2005 Mar;371(3):169-77. [Content Brief]
- [2]. Johnson KW, et al. 5-HT1F receptor agonists inhibit neurogenic dural inflammation in guinea pigs. Neuroreport. 1997 Jul 7;8(9-10):2237-40. [Content Brief]
