LY334370 hydrochloride
LY334370 hydrochloride is a selective 5-HT1F receptor agonist with a Kd value of 0.446 nM. LY334370 hydrochlorid has anti-migraine activity.
For research use only. We do not sell to patients.
- CAS No.: 199673-74-0
- Formula: C21H23ClFN3O
- Molecular Weight:387.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT1F Receptor |
5-HT1F Receptor 0.446 nM (Kd) |
Chemical Information
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CAS No. 199673-74-0
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Molecular Weight 387.88
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Formula C21H23ClFN3O
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SMILES
O=C(C1=CC=C(C=C1)F)NC2=CC3=C(NC=C3C4CCN(CC4)C)C=C2.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wainscott DB, et al. [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties. Naunyn Schmiedebergs Arch Pharmacol. 2005 Mar;371(3):169-77. [Content Brief]
[2]. Johnson KW, et al. 5-HT1F receptor agonists inhibit neurogenic dural inflammation in guinea pigs. Neuroreport. 1997 Jul 7;8(9-10):2237-40. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LY334370 hydrochloride Related Classifications
HY-103107A Related Classifications
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