LY334370 hydrochloride
LY334370 hydrochloride is a selective 5-HT1F receptor agonist with a Kd value of 0.446 nM. LY334370 hydrochlorid has anti-migraine activity.
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- No. CAS: 199673-74-0
- Fòrmula: C21H23ClFN3O
- Peso molecular:387.88
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
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5-HT1F Receptor 0.446 nM (Kd) |
Chemical Information
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No. CAS 199673-74-0
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Peso molecular 387.88
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Fòrmula C21H23ClFN3O
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SMILES
O=C(C1=CC=C(C=C1)F)NC2=CC3=C(NC=C3C4CCN(CC4)C)C=C2.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Wainscott DB, et al. [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties. Naunyn Schmiedebergs Arch Pharmacol. 2005 Mar;371(3):169-77. [Content Brief]
[2]. Johnson KW, et al. 5-HT1F receptor agonists inhibit neurogenic dural inflammation in guinea pigs. Neuroreport. 1997 Jul 7;8(9-10):2237-40. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)